RNA Details
Disease Name
liver cirrhosis
Tissue
liver
RNA Symbol
miR-17-5p
RNA ID
RNA Type
miRNA
Alteration Pattern
down regulation
Species
rattus norvegicus
Detection Methods
PCR; dual-lucimmunofluorescenceerase reporter assay; etc.
Target
WNT; B-CATENIN
Pathway
WNT SIGNALING PATHWAY; CATENIN BETA 1
PubMed ID
Title
MicroRNA-17-5p-activated Wnt/B-catenin pathway contributes to the progression of liver fibrosis
Year
2015
Function
"Increased expression of mir-17-5p, decreased expression of wif1, activation of wnt pathway, occurrence of fibrosis, and inhibition of mir-17-5p expression by salb."